BDBM464345 1-(3-fluoro-2- methylbenzyl)-3-(6- methoxy-5-(1H- pyrazol-4-yl)pyridin- 2-yl)-8-(3-(2- oxopyrrolidin-1- yl)propanoyl)-1,3,8- triazaspiro[4.5]decan- 2-one::US10787450, Example 227
SMILES COc1nc(ccc1-c1cn[nH]c1)N1CC2(CCN(CC2)C(=O)CCN2CCCC2=O)N(Cc2cccc(F)c2C)C1=O
InChI Key InChIKey=AHZBDFHYUCWDHZ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 464345
Affinity DataIC50: <3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair