BDBM464354 3-(4-(1H- pyrazol-4- yl)phenyl)- 1-(3- fluoro-5- methoxy- benzyl)-8- (oxetan-3- yl)-1,3,8- triazaspiro [4.5]decan- 2-one::US10787450, Example 236
SMILES COc1cc(F)cc(CN2C(=O)N(CC22CCN(CC2)C2COC2)c2ccc(cc2)-c2cn[nH]c2)c1
InChI Key InChIKey=RNNCEZWYOQVNEN-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 464354
Affinity DataIC50: <3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair