BDBM464389 US10787459, Example 3.00::US10787459, Example 4.00

SMILES CO[C@]12CN(C[C@@H]1CN(C2)C(=O)c1cc(OCC2CCOCC2)nc(c1)C1CC1)C(=O)N1CCc2[nH]nnc2C1

InChI Key InChIKey=KEOOODGLELKWNW-RBTNQOKQSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 464389   

TargetAtaxin-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM464389(US10787459, Example 3.00 | US10787459, Example 4.0...)
Affinity DataIC50:  10nMAssay Description:Assay working solutions were made as follows:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtaxin-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM464389(US10787459, Example 3.00 | US10787459, Example 4.0...)
Affinity DataIC50:  6nMAssay Description:Assay working solutions were made as follows:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent