BDBM464394 N-[1-(chloromethyl)-2-oxo-4-pyridyl]-2-(4-fluoro-2-methyl-phenoxy)-4-(trifluoromethyl)benzamide ::US10787472, Compound 2

SMILES Cc1cc(F)ccc1Oc1cc(ccc1C(=O)Nc1ccn(CCl)c(=O)c1)C(F)(F)F

InChI Key InChIKey=PRJUCGVKVMJHAQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 464394   

TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM464394(N-[1-(chloromethyl)-2-oxo-4-pyridyl]-2-(4-fluoro-2...)
Affinity DataIC50:  28nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent