BDBM464602 CIS-3-Acetyl-8-dimethylamino-8-phenyl-1,3-diazaspiro[4.5]decan-2-one::US10793556, Example SC_4031::US10793556, Example SC_4032

SMILES COC(=O)CCCN1C[C@]2(CC[C@@](CC2)(N(C)C)c2ccccc2)N(CC2CCC2)C1=O

InChI Key InChIKey=FYTOYUDVVMFIOF-WMPKNSHKSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 464602   

TargetNociceptin receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464602(CIS-3-Acetyl-8-dimethylamino-8-phenyl-1,3-diazaspi...)
Affinity DataKi:  119nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNociceptin receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464602(CIS-3-Acetyl-8-dimethylamino-8-phenyl-1,3-diazaspi...)
Affinity DataKi:  345nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464602(CIS-3-Acetyl-8-dimethylamino-8-phenyl-1,3-diazaspi...)
Affinity DataKi:  1.43E+3nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464602(CIS-3-Acetyl-8-dimethylamino-8-phenyl-1,3-diazaspi...)
Affinity DataKi:  8.53E+3nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent