BDBM464683 US10793563, Compound I-43::US10793563, Compound I-5::US10793563, Compound I-6

SMILES FC(F)(F)c1ccc2ncc(-c3nccc(n3)N3CCN4C(CNC4=O)C3)n2c1

InChI Key InChIKey=FTSNQHNMRFCHNQ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 464683   

TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM464683(US10793563, Compound I-43 | US10793563, Compound I...)
Affinity DataKi: <10nMAssay Description:An assay buffer containing GCN2 kinase and (RS)7 was prepared. 4.7 μL of this stock solution was placed per well of a black, low volume, 384-wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM464683(US10793563, Compound I-43 | US10793563, Compound I...)
Affinity DataKi:  55nMAssay Description:An assay buffer containing GCN2 kinase and (RS)7 was prepared. 4.7 μL of this stock solution was placed per well of a black, low volume, 384-wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM464683(US10793563, Compound I-43 | US10793563, Compound I...)
Affinity DataKi:  55nMAssay Description:An assay buffer containing GCN2 kinase and (RS)7 was prepared. 4.7 μL of this stock solution was placed per well of a black, low volume, 384-wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent