BDBM465337 US10793564, Compound 127::US11419869, Compound 127::US11560376, Compound 127

SMILES COC[C@@H](F)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ccncn1)C(O)=O

InChI Key InChIKey=AVAGDMNSAIAKBL-FPOVZHCZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 465337   

TargetIntegrin alpha-5/beta-6(Homo sapiens (Human))
Pliant Therapeutics

US Patent
LigandPNGBDBM465337(US10793564, Compound 127 | US11419869, Compound 12...)
Affinity DataIC50:  625nMAssay Description:Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25° C., overnight). The coating soluti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Pliant Therapeutics

US Patent
LigandPNGBDBM465337(US10793564, Compound 127 | US11419869, Compound 12...)
Affinity DataIC50:  625nMAssay Description:Microplates were coated with recombinant human integrin αvβ6 (2 μg/mL) in PBS (100 μL/well 25° C., overnight). The coating soluti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Pliant Therapeutics

US Patent
LigandPNGBDBM465337(US10793564, Compound 127 | US11419869, Compound 12...)
Affinity DataIC50:  625nMAssay Description:A third series of exemplary compounds was selected for testing in the solid phase integrin αvβ6 binding assay. The compounds tested were co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent