BDBM465355 (S)-4-((2-(dimethylamino)-2-oxoethyl) (4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl) butyl)amino)-2-((2-(trifluoromethyl)pyrimidin-4-yl) amino) butanoic Acid::US10793564, Compound 145::US11419869, Compound 145::US11560376, Compound 145::US20230271960, Compound 145::US20230293519, Compound 145
SMILES CN(C)C(=O)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ccnc(n1)C(F)(F)F)C(O)=O
InChI Key InChIKey=CVYGSDQSQKUUJT-IBGZPJMESA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 465355
Affinity DataIC50: <50nMAssay Description:Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25° C., overnight). The coating soluti...More data for this Ligand-Target Pair
Affinity DataIC50: <50nMAssay Description:Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25° C., overnight). The coating soluti...More data for this Ligand-Target Pair
Affinity DataIC50: <50nMAssay Description:Microplates were coated with recombinant human integrin alphavbeta6 (2 ug/mL) in PBS (100 uL/well 25 C., overnight). The coating solution was removed...More data for this Ligand-Target Pair
Affinity DataIC50: <50nMAssay Description:Microplates were coated with recombinant human integrin αvβ6 (2 μg/mL) in PBS (100 μL/well 25° C., overnight). The coating soluti...More data for this Ligand-Target Pair
Affinity DataIC50: <50nMAssay Description:A third series of exemplary compounds was selected for testing in the solid phase integrin αvβ6 binding assay. The compounds tested were co...More data for this Ligand-Target Pair