BDBM465463 (R)-1-(3-(3-(4- (phenoxymethyl)phenyl)- 1H-indazol-1-yl)piperidin-1-yl)prop- 2-en-1-one::US10793566, Compound 102

SMILES C=CC(=O)N1CCCC(C1)n1nc(-c2ccc(OCc3ccccc3)cc2)c2cnccc12

InChI Key InChIKey=YMDXTMKLLCNIIY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 465463   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Zibo Biopolar Changsheng Pharmaceutical

US Patent
LigandPNGBDBM465463((R)-1-(3-(3-(4- (phenoxymethyl)phenyl)- 1H-indazol...)
Affinity DataIC50:  55nMAssay Description:Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were performed in a reaction volume...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent