BDBM465479 1-((R)-3-(3-(4-(2-fluoro-3- methoxyphenoxy)phenyl)-7- methoxy-1H-pyrazolo[4,3- c]pyridin-1-yl)piperidin-1-yl)-2- hydroxypropan-1-one::US10793566, Compound 118

SMILES COc1cccc(Oc2ccc(cc2)-c2nn(C3CCCN(C3)C(=O)C(C)O)c3c(OC)cncc23)c1F

InChI Key InChIKey=WHHJLOKESSWXIM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 465479   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Zibo Biopolar Changsheng Pharmaceutical

US Patent
LigandPNGBDBM465479(1-((R)-3-(3-(4-(2-fluoro-3- methoxyphenoxy)phenyl)...)
Affinity DataIC50:  55nMAssay Description:Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were performed in a reaction volume...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent