BDBM465540 US10793568, Compound I-190

SMILES CC(C)CCS(=O)(=O)NC(=O)c1ccc(N2C[C@@H]3C[C@H]2C[C@H]3OCc2c(onc2-c2c(Cl)cccc2Cl)C2CC2)c(F)c1

InChI Key InChIKey=YBJSYYXLSLAYPO-NOMHHCBYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 465540   

TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465540(US10793568, Compound I-190)
Affinity DataEC50:  3.98nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent