BDBM465744 2-{3-[2-amino-6-(pyridin-4-yl)-7H- pyrrolo[2,3-d]pyrimidin-4-yl]-2- (hydroxymethyl)phenyl}-6-cyclopropyl- 8-fluoroisoquinolin-1(2H)-one::US10793575, Example 19
SMILES Nc1nc(-c2cccc(c2CO)-n2ccc3cc(cc(F)c3c2=O)C2CC2)c2cc([nH]c2n1)-c1ccncc1
InChI Key InChIKey=MCQWGHQRRKFOSK-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 465744
Affinity DataIC50: 0.140nMAssay Description:Inhibition of human BTK-A using phosphorylated substrate in presence of ATP by microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trade mark) MSA (commercially available kit manufactured by Carna Biosciences, In...More data for this Ligand-Target Pair