BDBM466122 US10793580, Example 222::[3-(1-ethyl-8-oxo-spiro[6,7- dihydro-4H-pyrazolo[3,4- c]azepine-5,4'-tetrahydro- pyran]-3-yl)-2,2-dimethyl- propyl] 4-(piperidine-1- carbonyl)benzoate

SMILES CCn1nc(CC(C)(C)COC(=O)c2ccc(cc2)C(=O)N2CCCCC2)c2CC3(CCOCC3)CNC(=O)c12

InChI Key InChIKey=JBTQRISPAMUIBM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 466122   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma

US Patent
LigandPNGBDBM466122(US10793580, Example 222 | [3-(1-ethyl-8-oxo-spiro[...)
Affinity DataIC50: <100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent