BDBM466254 US10793582, Example 70

SMILES FC(F)(F)COc1ncnc2nc(sc12)N1CCC[C@@H]1C(=O)NCc1ccccc1

InChI Key InChIKey=LMJYKETWOBHNKB-CYBMUJFWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 466254   

TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM466254(US10793582, Example 70)
Affinity DataIC50:  160nMAssay Description:To a reaction mixture (45 μL) containing 3.0 μmol/L kynurenine, 10 μmol/L pyridoxal phosphate, 2.0 ng/μL human recombinant KAT-II...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent