BDBM466862 US10800767, Example 15::US10800767, Example 5

SMILES CC(C)c1cc(Oc2c(Cl)cc(NCc3noc(=O)[nH]3)cc2Cl)n[nH]c1=O

InChI Key InChIKey=PKZQKRHFNDZRHB-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 466862   

TargetThyroid hormone receptor beta(Homo sapiens (Human))
Terns

US Patent
LigandPNGBDBM466862(US10800767, Example 15 | US10800767, Example 5)
Affinity DataEC50:  74.2nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen™ TR-FRET Thyroid Receptor beta Coactivator Assay ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Terns

US Patent
LigandPNGBDBM466862(US10800767, Example 15 | US10800767, Example 5)
Affinity DataEC50:  102nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen™ TR-FRET Thyroid Receptor beta Coactivator Assay ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Terns

US Patent
LigandPNGBDBM466862(US10800767, Example 15 | US10800767, Example 5)
Affinity DataEC50:  31.5nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen™ TR-FRET Thyroid Receptor beta Coactivator Assay ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Terns

US Patent
LigandPNGBDBM466862(US10800767, Example 15 | US10800767, Example 5)
Affinity DataEC50:  469nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen™ TR-FRET Thyroid Receptor beta Coactivator Assay ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent