BDBM466952 7-(Benzo[d][1,3]dioxol-5-yl)- 3-((2,2-difluorocyclopropyl) methyl)-[1,2,4]triazole [4,3-a]pyridine::US10800776, Example 35

SMILES FC1(F)CC1Cc1nnc2cc(ccn12)-c1ccc2OCOc2c1

InChI Key InChIKey=UJURXKLCXJFZLB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 466952   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM466952(7-(Benzo[d][1,3]dioxol-5-yl)- 3-((2,2-difluorocycl...)
Affinity DataIC50: >4.00E+4nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM466952(7-(Benzo[d][1,3]dioxol-5-yl)- 3-((2,2-difluorocycl...)
Affinity DataEC50:  108nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent