BDBM467004 US10800778, Comparator 99

SMILES OC(=O)C(F)ON1[C@H]2CN([C@@H](CC2)C(=O)NC2CCNCC2)C1=O

InChI Key InChIKey=RMNUWMLNSDZJHP-YVNMAJEFSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 467004   

TargetBeta-lactamase TEM(Escherichia coli)
Entasis Therapeutics

US Patent
LigandPNGBDBM467004(US10800778, Comparator 99)
Affinity DataIC50:  30nMAssay Description:A buffer consisting of 0.1 M sodium phosphate (pH 7.0), 10 mM NaHCO3, and 0.005% Triton X-100 was used for all enzymes. The chromogenic substrate nit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-lactamase(Klebsiella pneumoniae)
Entasis Therapeutics

US Patent
LigandPNGBDBM467004(US10800778, Comparator 99)
Affinity DataIC50:  8.20E+4nMAssay Description:A buffer consisting of 0.1 M sodium phosphate (pH 7.0), 10 mM NaHCO3, and 0.005% Triton X-100 was used for all enzymes. The chromogenic substrate nit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-lactamase(Escherichia coli)
Entasis Therapeutics

US Patent
LigandPNGBDBM467004(US10800778, Comparator 99)
Affinity DataIC50:  1.60E+3nMAssay Description:A buffer consisting of 0.1 M sodium phosphate (pH 7.0), 10 mM NaHCO3, and 0.005% Triton X-100 was used for all enzymes. The chromogenic substrate nit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent