BDBM467091 US10800784, Example 78

SMILES C[C@H]1CN(Cc2cnc(n12)[C@@](C)(O)C(F)(F)F)C(=O)c1ccnc(-c2ccc(cc2)C#N)c1F

InChI Key InChIKey=SDYHYNUKUWSPFA-WHEQGISXSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 467091   

LigandPNGBDBM467091(US10800784, Example 78)
Affinity DataIC50:  7nMAssay Description:In the case of human PDHK2 (hPDHK2, NCBI Reference Database Accession number NM_002611.4), modified hPDHK2 cDNA wherein FLAG-Tag sequence was added t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM467091(US10800784, Example 78)
Affinity DataIC50:  4nMAssay Description:In the case of human PDHK1 (hPDHK1, NCBI Reference Database Accession number NM_002610.3), a 1.3 kbp fragment encoding this protein was isolated from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent