BDBM467235 (R)-7-amino-3-(1-(but-2-ynoyl)piperidin-3-yl)-1- (4-(2,6-difluorophenoxy)phenyl)-1,5-dihydro- 4H-pyrazolo[3,4-d]pyridazin-4-one::US10800785, Example 85

SMILES CC#CC(=O)N1CCC[C@H](C1)c1nn(-c2ccc(Oc3c(F)cccc3F)cc2)c2c(N)n[nH]c(=O)c12

InChI Key InChIKey=AWCFRBYIWQIPRP-OAHLLOKOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 467235   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM467235((R)-7-amino-3-(1-(but-2-ynoyl)piperidin-3-yl)-1- (...)
Affinity DataIC50:  435nMAssay Description:MTS testing kit was purchased from Promega. The DMEM, Fetal bovine serum and Penicillin-Streptomycin were purchased from Gibco. Dimethyl sulfoxide (D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM467235((R)-7-amino-3-(1-(but-2-ynoyl)piperidin-3-yl)-1- (...)
Affinity DataIC50:  435nMAssay Description:MTS testing kit was purchased from Promega. The DMEM, Fetal bovine serum and Penicillin-Streptomycin were purchased from Gibco. Dimethyl sulfoxide (D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent