BDBM467240 3-(1-acryloylpyrrolidin-3-yl)-7-amino-1-(4-(2,6-difluorophenoxy)phenyl)-1,5-dihydro-4H-pyrrolo[2,3-d]pyridazin-4-one ::US10800785, Example 3

SMILES Nc1n[nH]c(=O)c2c(cn(-c3ccc(Oc4c(F)cccc4F)cc3)c12)C1CCN(C1)C(=O)C=C

InChI Key InChIKey=YXDXKUQNQVWOTL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 467240   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM467240(3-(1-acryloylpyrrolidin-3-yl)-7-amino-1-(4-(2,6-di...)
Affinity DataIC50:  147nMAssay Description:MTS testing kit was purchased from Promega. The DMEM, Fetal bovine serum and Penicillin-Streptomycin were purchased from Gibco. Dimethyl sulfoxide (D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM467240(3-(1-acryloylpyrrolidin-3-yl)-7-amino-1-(4-(2,6-di...)
Affinity DataIC50:  147nMAssay Description:MTS testing kit was purchased from Promega. The DMEM, Fetal bovine serum and Penicillin-Streptomycin were purchased from Gibco. Dimethyl sulfoxide (D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent