BDBM468306 2-(3-{2-amino-6-[2- (methylamino)pyridin- 4-yl]-7H-pyrrolo[2,3- d]pyrimidin-4-yl}-2- (hydroxy- methyl)phenyl)-6- cyclopropyl-8- fluoroisoquinolin- 1(2H)-one::US10793575, Example 50

SMILES CNc1cc(ccn1)-c1cc2c(nc(N)nc2[nH]1)-c1cccc(c1CO)-n1ccc2cc(cc(F)c2c1=O)C1CC1

InChI Key InChIKey=RZPMQEOKYLYKOO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 468306   

TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Carna Biosciences

US Patent
LigandPNGBDBM468306(2-(3-{2-amino-6-[2- (methylamino)pyridin- 4-yl]-7H...)
Affinity DataIC50:  1.60nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Carna Biosciences

US Patent
LigandPNGBDBM468306(2-(3-{2-amino-6-[2- (methylamino)pyridin- 4-yl]-7H...)
Affinity DataIC50:  0.770nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trade mark) MSA (commercially available kit manufactured by Carna Biosciences, In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent