BDBM468308 2-[3-(2-amino-6-{4- [(diethyl- amino)methyl]phenyl}- 7H-pyrrolo[2,3- d]pyrimidin-4-yl)-2- (hydroxy- methyl)phenyl]-6- cyclopropyl- 8-fluoroisoquinolin- 1(2H)-one::US10793575, Example 52

SMILES CCN(CC)Cc1ccc(cc1)-c1cc2c(nc(N)nc2[nH]1)-c1cccc(c1CO)-n1ccc2cc(cc(F)c2c1=O)C1CC1

InChI Key InChIKey=NAYVCYNRDSSGLK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 468308   

TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Carna Biosciences

US Patent
LigandPNGBDBM468308(2-[3-(2-amino-6-{4- [(diethyl- amino)methyl]phenyl...)
Affinity DataIC50:  0.760nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Carna Biosciences

US Patent
LigandPNGBDBM468308(2-[3-(2-amino-6-{4- [(diethyl- amino)methyl]phenyl...)
Affinity DataIC50:  0.430nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trade mark) MSA (commercially available kit manufactured by Carna Biosciences, In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent