BDBM468311 2-{3-[2-amino-6-(4- {[4-(2-hydroxy- ethyl)piperazin-1- yl]methyl}phenyl)- 7H-pyrrolo[2,3- d]pyrimidin-4-yl]-2- (hydroxy- methyl)phenyl}-6- cyclopropyl- 8-fluoroisoquinolin- 1(2H)-one::US10793575, Example 61

SMILES Nc1nc(-c2cccc(c2CO)-n2ccc3cc(cc(F)c3c2=O)C2CC2)c2cc([nH]c2n1)-c1ccc(CN2CCN(CCO)CC2)cc1

InChI Key InChIKey=BZFILMQHPUXYPI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 468311   

TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Carna Biosciences

US Patent
LigandPNGBDBM468311(2-{3-[2-amino-6-(4- {[4-(2-hydroxy- ethyl)piperazi...)
Affinity DataIC50:  0.570nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Carna Biosciences

US Patent
LigandPNGBDBM468311(2-{3-[2-amino-6-(4- {[4-(2-hydroxy- ethyl)piperazi...)
Affinity DataIC50:  0.360nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trade mark) MSA (commercially available kit manufactured by Carna Biosciences, In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent