BDBM468340 US10806720, Compound 1021::US11230523, Compound 1021::US11648234, Compound 1021

SMILES C[C@](O)(Cn1ccc(F)c1)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=JWYXFBRAUPDMTC-HNNXBMFYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 468340   

TargetAndrogen receptor(Homo sapiens (Human))
University Of Tennessee Research Foundation

US Patent
LigandPNGBDBM468340(US10806720, Compound 1021 | US11230523, Compound 1...)
Affinity DataKi:  633nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor [633-919](Homo sapiens (Human))
University Of Tennessee Research Foundation

US Patent
LigandPNGBDBM468340(US10806720, Compound 1021 | US11230523, Compound 1...)
Affinity DataKi:  633nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468340(US10806720, Compound 1021 | US11230523, Compound 1...)
Affinity DataKi:  633nMAssay Description:Inhibition of [3H] MIB binding to rat prostate androgen receptor LBD by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAndrogen receptor [633-919](Homo sapiens (Human))
University Of Tennessee Research Foundation

US Patent
LigandPNGBDBM468340(US10806720, Compound 1021 | US11230523, Compound 1...)
Affinity DataKi:  633nMAssay Description:hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD was combin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent