BDBM468347 US10806720, Compound 1030::US11648234, Compound 1030

SMILES CC(C)(C)OC(=O)Nc1cnn(C[C@](C)(O)C(=O)Nc2cnc(C#N)c(c2)C(F)(F)F)c1

InChI Key InChIKey=SXXVPIPXOUJQCN-SFHVURJKSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 468347   

TargetAndrogen receptor(Rattus norvegicus (Rat))
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468347(US10806720, Compound 1030 | US11648234, Compound 1...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-MIB from wild-type rat AR LBD measured after 16 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAndrogen receptor [633-919](Homo sapiens (Human))
University Of Tennessee Research Foundation

US Patent
LigandPNGBDBM468347(US10806720, Compound 1030 | US11648234, Compound 1...)
Affinity DataIC50:  6.11E+3nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
University Of Tennessee Research Foundation

US Patent
LigandPNGBDBM468347(US10806720, Compound 1030 | US11648234, Compound 1...)
Affinity DataIC50:  6.11E+3nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
University Of Tennessee Research Foundation

US Patent
LigandPNGBDBM468347(US10806720, Compound 1030 | US11648234, Compound 1...)
Affinity DataIC50:  6.11E+3nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed