BDBM468367 (6R,9S)- or (6S,9R)- 4-(1-(difluoromethyl)- 1H-pyrazol-4-yl)- 6,7,8,9-tetrahydro-5H- 6,9- epoxycyclohepta[b] pyridine-2-carboxamide::US10806724, Example 1-5A

SMILES NC(=O)c1cc(-c2cnn(c2)C(F)F)c2C[C@H]3CC[C@H](O3)c2n1

InChI Key InChIKey=KITCKKYBIDIUCD-PELKAZGASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 468367   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM468367((6R,9S)- or (6S,9R)- 4-(1-(difluoromethyl)- 1H-pyr...)
Affinity DataIC50: >3.00E+3nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent