BDBM468427 US10806785, Example 71::cis-4-((2-((2,2'-dichloro-3'- (5-(cyclopropylmethyl)-1- methyl-4,5,6,7- tetrahydro-1H- imidazo[4,5-c]pyridine-2- carboxamido)-[1,1'- biphenyl]-3-yl)carbamoyl)- 1-methyl-1,4,6,7-tetrahydro- 5H-imidazo[4,5-c]pyridin- 5-yl)methyl)cyclohexane- 1-carboxylic acid

SMILES Cn1c2CCN(CC3CC3)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@H](CC4)C(O)=O)CCc3n2C)c1Cl

InChI Key InChIKey=FKYFHUBPUGSKHV-PLQXJYEYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 468427   

TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM468427(US10806785, Example 71 | cis-4-((2-((2,2'-dichloro...)
Affinity DataIC50: <0.100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent