BDBM468524 US10806785, Example 153::trans-4-(2-(2- ((2-chloro-2'- cyano-3'- (1-methyl-5- (tetrahydro- 2H-pyran-4-yl)- 4,5,6,7- tetrahydro-1H- imidazo[4,5-c] pyridine-2- carboxamido)- [1,1'-biphenyl]- 3-yl) carbamoyl)- 1-methyl- 1,4,6,7- tetrahydro-5H- imidazo[4,5-c] pyridin-5- yl)ethyl) cyclohexane-1- carboxylic acid

SMILES Cn1c2CCN(CC[C@H]3CC[C@@H](CC3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)c1C#N

InChI Key InChIKey=GPFRCZMAWXHVGC-MCZWQBSQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 468524   

TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM468524(US10806785, Example 153 | trans-4-(2-(2- ((2-chlor...)
Affinity DataIC50: <0.100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent