BDBM468985 2-methyl-4-(2-methyl-1,1-dioxo-3H-1,2- benzothiazol-6-yl)isoquinolin-1-one::US10807982, Example 1

SMILES CN1Cc2ccc(cc2S1(=O)=O)-c1cn(C)c(=O)c2ccccc12

InChI Key InChIKey=PGBBIPXLGUYYEM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 468985   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM468985(2-methyl-4-(2-methyl-1,1-dioxo-3H-1,2- benzothiazo...)
Affinity DataIC50:  2.75E+3nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent