BDBM469069 US10807980, Compound 6

SMILES CCS(=O)(=O)c1ccc(CNC(=O)c2cnc3[C@H](C(C)C)N(Cc3c2)c2nccc(n2)C(F)(F)F)nc1

InChI Key InChIKey=UVZNTEKWMBWHJL-NRFANRHFSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 469069   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM469069(US10807980, Compound 6)
Affinity DataKi: <100nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM469069(US10807980, Compound 6)
Affinity DataIC50: >1.00E+3nMAssay Description:Compounds of the present invention were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent