BDBM469072 4-[5-(cyclopropylmethoxy)-2-methyl-1,1-dioxo- 3H-1,2-benzothiazol-6-yl]-2- methylisoquinolin-1-one::US10807982, Example 6

SMILES CN1Cc2cc(OCC3CC3)c(cc2S1(=O)=O)-c1cn(C)c(=O)c2ccccc12

InChI Key InChIKey=HCGHJQUBUGIUBL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469072   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469072(4-[5-(cyclopropylmethoxy)-2-methyl-1,1-dioxo- 3H-1...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent