BDBM469084 1,3-dimethyl-5-[2-methyl-1,1-dioxo-5-(2,2,2- trifluoroethoxy)-3H-1,2-benzothiazol-6- yl]pyridin-2-one::US10807982, Example 9

SMILES CN1Cc2cc(OCC(F)(F)F)c(cc2S1(=O)=O)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=MLBJWYFYMHNZSA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469084   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469084(1,3-dimethyl-5-[2-methyl-1,1-dioxo-5-(2,2,2- trifl...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent