BDBM469097 US10807974, Example 116::US10995088, Example 116::US11608330, Example 116

SMILES Cn1cc(cn1)-c1cccc(c1)S(=O)(=O)c1cnc(CN)s1

InChI Key InChIKey=ZFLLYOVLKLVXCJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 469097   

TargetLysyl oxidase homolog 2(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469097(US10807974, Example 116 | US10995088, Example 116 ...)
Affinity DataIC50:  74nMAssay Description:LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 hours at room temp on a plate shaker.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmiloride-sensitive amine oxidase [copper-containing](Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469097(US10807974, Example 116 | US10995088, Example 116 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Promega ROS-Glo H2O2 Assay Kit, 50 ml. Cat No. G8821.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469097(US10807974, Example 116 | US10995088, Example 116 ...)
Affinity DataIC50: >1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469097(US10807974, Example 116 | US10995088, Example 116 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:ReagentsPromega ROS-Glo H2O2 Assay Kit, 50 ml. Cat No. G8821Inhibitors (Test Compounds):10 mM stock diluted to 10, 3, 1, 0.3, 0.1, 0.03, 0.01, 0.003,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469097(US10807974, Example 116 | US10995088, Example 116 ...)
Affinity DataIC50:  74nMAssay Description:MAO-Glo Assay Kit: Promega, Cat No. V1402MAO-A Enzyme: Promega, Cat No. V1452Clorgyline: Sigma, Cat No. M3778 (50 mg)Assay Plates:96 well white polys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469097(US10807974, Example 116 | US10995088, Example 116 ...)
Affinity DataIC50:  74nMAssay Description:10. Incubate for 20 hrs at room temp on a plate shaker, protected from light.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent