BDBM469121 5-(2-ethyl-5-methylsulfonyl-1-benzofuran-7-yl)- 1,3-dimethylpyridin-2-one::US10807982, Example 21

SMILES CCc1cc2cc(cc(-c3cc(C)c(=O)n(C)c3)c2o1)S(C)(=O)=O

InChI Key InChIKey=MDSONSDVBTYUBR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469121   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469121(5-(2-ethyl-5-methylsulfonyl-1-benzofuran-7-yl)- 1,...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent