BDBM469126 5-(2-cyclopropyl-5-methylsulfonyl-1-benzofuran- 7-yl)-1,3-dimethylpyridin-2-one::US10807982, Example 23

SMILES Cc1cc(cn(C)c1=O)-c1cc(cc2cc(oc12)C1CC1)S(C)(=O)=O

InChI Key InChIKey=HSBFMSYLCIMBKP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469126   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469126(5-(2-cyclopropyl-5-methylsulfonyl-1-benzofuran- 7-...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent