BDBM469136 4-(2-cyclopropyl-5-ethylsulfonyl-1-benzofuran- 7-yl)-2-methylisoquinolin-1-one::US10807982, Example 24

SMILES Cn1cc(-c2cc(cc3cc(oc23)C2CC2)S(C)(=O)=O)c2ccccc2c1=O

InChI Key InChIKey=BMVGRYYCVHUNTL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469136   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469136(4-(2-cyclopropyl-5-ethylsulfonyl-1-benzofuran- 7-y...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent