BDBM469142 1,3-dimethyl-5-(5-methylsulfonyl-2-phenyl-1- benzofuran-7-yl)pyridin-2-one::US10807982, Example 25

SMILES Cc1cc(cn(C)c1=O)-c1cc(cc2cc(oc12)-c1ccccc1)S(C)(=O)=O

InChI Key InChIKey=WNFZVQDLQVHBHD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469142   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469142(1,3-dimethyl-5-(5-methylsulfonyl-2-phenyl-1- benzo...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent