BDBM469158 N-[1-[(4-fluorophenyl)methyl]-6-(5-methoxy-1- methyl-6-oxopyridin-3-yl)-2-methylbenzimidazol- 4-yl]methanesulfonamide::US10807982, Example 38

SMILES COc1cc(cn(C)c1=O)-c1cc(NS(C)(=O)=O)c2nc(C)n(Cc3ccc(F)cc3)c2c1

InChI Key InChIKey=SMXJKBNPHKWEDB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469158   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469158(N-[1-[(4-fluorophenyl)methyl]-6-(5-methoxy-1- meth...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent