BDBM469160 N-[1-butyl-6-(1,5-dimethyl-6-oxopyridin-3- yl)benzimidazol-4-yl]ethanesulfonamide::US10807982, Example 40

SMILES CCCCn1cnc2c(NS(=O)(=O)CC)cc(cc12)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=UDHKQTCAQRTSNH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469160   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469160(N-[1-butyl-6-(1,5-dimethyl-6-oxopyridin-3- yl)benz...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent