BDBM469163 N-[6-(1,5-dimethyl-6-oxopyridin-3-yl)-1-[(4- fluorophenyl)methyl]indazol-4- yl]ethanesulfonamide::US10807982, Example 43

SMILES CCS(=O)(=O)Nc1cc(cc2n(Cc3ccc(F)cc3)ncc12)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=UPRXDQXRQLZTBQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469163   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469163(N-[6-(1,5-dimethyl-6-oxopyridin-3-yl)-1-[(4- fluor...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent