BDBM469173 N-[2-cyclopentyl-7-(2-methyl-1-oxoisoquinolin-4- yl)-1,3-benzoxazol-5-yl]ethanesulfonamide::US10807982, Example 53

SMILES CCS(=O)(=O)Nc1cc(-c2cn(C)c(=O)c3ccccc23)c2oc(nc2c1)C1CCCC1

InChI Key InChIKey=VUNICRAJLKWEQG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469173   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469173(N-[2-cyclopentyl-7-(2-methyl-1-oxoisoquinolin-4- y...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent