BDBM469177 N-[2-cyclopentyl-7-(5-methoxy-1-methyl-6- oxopyridin-3-yl)-1,3-benzoxazol-5- yl]ethanesulfonamide::US10807982, Example 57

SMILES CCS(=O)(=O)Nc1cc(-c2cc(OC)c(=O)n(C)c2)c2oc(nc2c1)C1CCCC1

InChI Key InChIKey=TYHDAJBFQXYGBK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469177   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469177(N-[2-cyclopentyl-7-(5-methoxy-1-methyl-6- oxopyrid...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent