BDBM469190 5-[3-(cyclopropylmethyl)-7-ethylsulfonyl-2- methylbenzimidazol-5-yl]-3-methoxy-1- methylpyridin-2-one::US10807982, Example 70

SMILES CCS(=O)(=O)c1cc(cc2n(CC3CC3)c(C)nc12)-c1cc(OC)c(=O)n(C)c1

InChI Key InChIKey=OMLUYJWWXPMJJZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469190   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469190(5-[3-(cyclopropylmethyl)-7-ethylsulfonyl-2- methyl...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent