BDBM469197 4-[1-(cyclopropylmethyl)-4-methylsulfonylindol- 2-yl]-2-methylisoquinolin-1-one::US10807982, Example 78

SMILES Cn1cc(-c2cc3c(cccc3n2CC2CC2)S(C)(=O)=O)c2ccccc2c1=O

InChI Key InChIKey=PPIGOOJJBPANIV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469197   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469197(4-[1-(cyclopropylmethyl)-4-methylsulfonylindol- 2-...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent