BDBM469199 N-[2-cyclopropyl-7-(1,5-dimethyl-6-oxopyridin- 3-yl)-1-benzofuran-5-yl]methanesulfonamide::US10807982, Example 80

SMILES Cc1cc(cn(C)c1=O)-c1cc(NS(C)(=O)=O)cc2cc(oc12)C1CC1

InChI Key InChIKey=LHEMTKPEUZEKNE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469199   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469199(N-[2-cyclopropyl-7-(1,5-dimethyl-6-oxopyridin- 3-y...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent