BDBM469203 N-[7-(2-methyl-1-oxoisoquinolin-4-yl)-2-phenyl- 1-benzofuran-5-yl]methanesulfonamide::US10807982, Example 84

SMILES Cn1cc(-c2cc(NS(C)(=O)=O)cc3cc(oc23)-c2ccccc2)c2ccccc2c1=O

InChI Key InChIKey=YBIFRFJARITXLY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469203   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469203(N-[7-(2-methyl-1-oxoisoquinolin-4-yl)-2-phenyl- 1-...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent