BDBM469210 5-[1-(2-cyclopropylethyl)-4-methylsulfonylindol- 2-yl]-3-methoxy-1-methylpyridin-2-one::US10807982, Example 91

SMILES COc1cc(cn(C)c1=O)-c1cc2c(cccc2n1CCC1CC1)S(C)(=O)=O

InChI Key InChIKey=BCDGLJJQDDUILV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469210   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469210(5-[1-(2-cyclopropylethyl)-4-methylsulfonylindol- 2...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent