BDBM469216 5-[3-(cyclopropylmethyl)-2-ethoxy-7- (methylsulfonylmethyl)benzimidazol-5-yl]-1,3- dimethylpyridin-2-one::US10807982, Example 97

SMILES CCOc1nc2c(CS(C)(=O)=O)cc(cc2n1CC1CC1)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=QHKMXVMYKLXAGR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469216   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469216(5-[3-(cyclopropylmethyl)-2-ethoxy-7- (methylsulfon...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent