BDBM469217 5-[3-(cyclopropylmethyl)-2-ethoxy-7- (methylsulfonylmethyl)benzimidazol-5-yl]-3- methoxy-1-methylpyridin-2-one::US10807982, Example 98

SMILES CCOc1nc2c(CS(C)(=O)=O)cc(cc2n1CC1CC1)-c1cc(OC)c(=O)n(C)c1

InChI Key InChIKey=HVWHLXVJFVUUBU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469217   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469217(5-[3-(cyclopropylmethyl)-2-ethoxy-7- (methylsulfon...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent