BDBM469219 5-[2-cyclopropyl-5-(ethylsulfonylmethyl)-1,3- benzoxazol-7-yl]-3-methoxy-1- methylpyridin-2-one::US10807982, Example 100

SMILES CCS(=O)(=O)Cc1cc(-c2cc(OC)c(=O)n(C)c2)c2oc(nc2c1)C1CC1

InChI Key InChIKey=ITDJQMDKFBKZOG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469219   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469219(5-[2-cyclopropyl-5-(ethylsulfonylmethyl)-1,3- benz...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent